邢 琦
职 称: 助教
邮 箱: 694445508@qq.com
教育经历(从大学开始)
2006年9月—2010年7月,山西大学,应用化学专业,本科
2010年9月—2015年12月,中国科学院兰州化学物理研究所,物理化学专业,硕博连读
2017年8月—2019年8月,香港理工大学应用生物及化学科技学系
,博士后
教学工作
1.主讲课程
暂无。
科研工作
1.研究方向
(1)绿色催化;(2) 功能高分子材料;(3) 肿瘤精准治疗药物研发
2.科研成果
主持国家自然科学基金青年项目,中科院西部之光青年学者B类项目及深圳先进技术研究院优青项目。共发表SCI论文及论著17篇。其中,以第一作者或通讯作者(含共同)在J. Am. Chem. Soc., Nat. Commun., Org. Lett., Biomacromolecules等国际知名学术期刊上发表文章15篇,申请国家发明专利4项。
代表性学术论文:
(1) Lei Luo, Fei Liu, Zhiying Li, Siyuan Yue, Liang Wang, Shiling Zhang, Shanmeng Lin, Jinyan Luo, Meng Wang, Yichuan Zhang, Mohamed Abdelrahim, Qi Xing*, Jin Geng*. Amphiphilic Block Copolymers Containing Benzenesulfonyl Azide Groups as Visible Light-Responsive Drug Carriers for Image-Guided Delivery. Biomacromolecules, 2024, 25, 1671–1681.
(2) Lan Lou, Shiling Zhang, Al-Hassan S. Mahdy, Meng Wang, Kai Li,* Qi Xing,* Jin Geng*. Thermal- and Oxidation Dual-Responsive Random Copolymer Self-Assembly of Nanostructures. Polym. Chem., 2024, 15, 1339–1346.
(3) Liang Wang, Ghada E. Khedr, Lei Luo, Shiling Zhang, Zhiying Li, Shanmeng Lin, Jinyan Luo, Qi Xing*, Jin Geng*. Investigating AIE Behaviors of Amphiphilic AIEgenbased Polymers Through Self-Assembly Architectures and Hydrophobic Core Arrangements. Polym. Chem., 2023, 14, 3749–3760.
(4) Kui Tan, Jiaan He, Zhilin Mu, Ibrahim M. Ammar, Chao Che*, Jin Geng*, and Qi Xing*. Visible-Light-Promoted C(sp3)–C(sp3) Cross-Coupling of Amino Acids and Aryl Trifluoromethyl Ketones Through Simultaneous Decarboxylation and Defluorination. Org. Lett., 2023, 25, 8733–8738
(5) Qi Xing*, Ding Jiang, Jiayin Zhang, Liangyu Guan, Ting Li, Yi Zhao, Man Di, Huangcan Chen, Chao Che*, Zhendong Zhu*. Combining Visible-Light Induction and Copper Catalysis for Chemo-Selective Nitrene Transfer: A Practical Strategy for Late-Stage Amination of Natural Products. Commun. Chem., 2022, 5, 79.
(6) Chengtao Yue, Qi Xing (Joint first authors), Peng Sun, Zelun Zhao, Hui Lv, Fuwei Li*. Enhancing Stability by Trapping Palladium inside N-Heterocyclic Carbene-Functionalized Hypercrosslinked Polymers for Heterogeneous C–C Bond Formations. Nat. Commun., 2021, 12, 1875–1889.
(7) Qi Xing, Chun-Ming Chan, Yiu-Wai Yeung, and Wing-Yiu Yu*. Ruthenium(II)-Catalyzed Enantioselective γ-Lactams Formation by Intramolecular C–H Amidation of 1,4,2-Dioxazol-5-ones. J. Am. Chem. Soc., 2019, 141, 3849–3853.
(8) Chun-Ming Chan, Qi Xing (Joint first authors), Yip-Chi Chow, Sing-Fung Hung, and Wing-Yiu Yu*. Photoredox Decarboxylative C(sp3)−N Coupling of α-Diazoacetates with Alkyl N-Hydroxyphthalimide Esters for Diversified Synthesis of Functionalized N-Alkyl Hydrazones. Org. Lett. 2019, 21, 8037−8043.
(9) Qi Xing, Hui Lv, Chungu Xia, Fuwei Li*. Palladium-Catalyzed Intermolecular Carbonylative Cross-Coupling of Heteroaryl C(sp2)–H Bonds with Amines: An Efficient Strategy for Oxidative Aminocarbonylation of Azoles. Chem. Commun., 2017, 53, 6914−6917.
(10) Qi Xing, Hui Lv, Chungu Xia, Fuwei Li*. Iron-Catalyzed Aerobic Oxidative Cleavage of the C–C σ-Bond Using Air as the Oxidant: Chemoselective Synthesis of Carbon Chain-Shortened Aldehydes, Ketones and 1,2-Dicarbonyl Compounds. Chem. Commun., 2016, 52, 489−492.
发明专利:
(1) 耿晋,邢琦,付臻鹏,杨金莹,高权,何家安,冯桂珍,周美妮,肖海琪,陈佳涣,刘金超,偶氮化合物、偶氮前药化合物、药物组合物、高能射线响应脂质分子以及高能射线响应脂质体,授权号:CN118146115B。
(2) 耿晋,邢琦,杨金莹,高权,何家安,黄桂媛,冯桂珍,牟智霖,岳思源,周美妮,肖海琪,付臻鹏,一类叠氮前药化合物、制备方法及其应用,申请公布号:CN119874789A
(3) 朱振东,邢琦,车超,黎婷,蒋顶,张家银,张传冰,杨震,氮杂螺环、多环穿心莲内酯类化合物及其制备方法、药物组合物及应用,授权号:CN112645937B
(4) 朱振东,车超,蒋顶,邢琦,张家银,黎婷,林光,杨震,穿心莲内酯类化合物及其制备方法、药物组合物和其在抗肿瘤药物中的应用,授权号:CN111518085B