职 称:助教
邮 箱:669209352@qq.com; szxydp@163.com
教育经历(从大学开始)
2010年9月—2014年7月,宿州学院,化学工程与工艺专业,本科
2015年9月—2017年7月,南京农业大学,化学工程专业,硕士
2018年9月—2022年6月,南京农业大学,天然产物化学专业,博士
2022年9月—2025年11月,南京农业大学,博士后
教学工作
1.主讲课程
暂无。
科研工作
1.研究方向
(1) 天然源农药的合成及结构改造;(2) 新型高效的绿色化学农药的分子设计、合成及生物活性;(3) 绿色合成有机方法学研究
2.科研成果
主持江苏省自然科学基金青年项目(2025-2028)、江苏省卓越博士后计划项目(已结题),发表学术论文32余篇,申请国家发明专利1项。
代表性学术论文:
(1) Peng Dai, Zihua Ma, Kaili Xie, Yufei Li, Yujie Zhang, Chenxiao Li, Yafang Sun, Yu-Cheng Gu, Qing Xia* and Weihua Zhang*, Discovery of Novel Pyrazole/Thiazole Derivatives Containing Cyano/Thiocyanato Groups as Fungicide Candidates, J. Agric. Food Chem. 2025, 73 (10), 6231-6240.
(2) Peng Dai, Yufei Li, Zihua Ma, Jian Jiao, Qing Xia* and Weihua Zhang*, Design, Synthesis, Antifungal Evaluation, and Three-Dimensional Quantitative Structure−Activity Relationship of Novel 5‑Sulfonyl-1,3,4-thiadiazole Flavonoids. J. Agric. Food Chem. 2024, 72 (39), 21419−21428.
(3) Peng Dai, Zihua Ma, Xiang Yu, Wei Chen, Peng Teng, Yufei Li, Zhaojun Xu, Qing Xia, Zewen Liu, and Weihua Zhang*, 3D-QSAR-Directed Synthesis of Halogenated Coumarin-3-Hydrazide Derivatives: Unveiling Their Potential as SDHI Antifungal Agents, J. Agric. Food Chem. 2024, 72 (21), 11938-11948.
(4) Peng Dai, Jian Jiao, Yufei Li, Peng Teng, Qingqing Wang, Yuchuan Zhu, and Weihua Zhang*, Novel 5‑Sulfonyl-1,3,4- thiadiazole-Substituted Flavonoids as Potential Bactericides and Fungicides: Design, Synthesis, ThreeDimensional Quantitative Structure−Activity Relationship Studies, J. Agric. Food Chem. 2024, 72 (12), 6672-6683.
(5) Peng Dai, Qingqing Wang, Peng Teng, Jian Jiao, Yufei Li, Qing Xia* and Weihua Zhang*, Design, Synthesis, Antifungal Activity, and 3D-QASR of Novel Oxime Ether-Containing Coumarin Derivatives as Potential Fungicides, J. Agric. Food Chem. 2024, 72 (11), 5983-5992.
(6) Peng Dai, Zihua Ma, Yuncong Dang, Jiaxuan Huang, Huizhen Xue, Yafang Sun, Yu-Cheng Gu, Qing Xia* and Weihua Zhang*, Design and synthesis of camphor-thiazole derivatives as potent antifungal agents: structure–activity relationship and preliminary mechanistic study, Pest Manag. Sci. 2025, 81 (3), 1592-1602.
(7) Peng Dai, Zihua Ma, Guangfu Yi, Yufei Li, Kaili Xie, Yafang Sun, Qing Xia, Zewen Liu and Weihua Zhang*, Rational design and discovery of novel hydrazide derivatives as potent succinate dehydrogenase inhibitors inspired by natural D/L-camphor, Pest Manag. Sci. 2025, 81 (2), 786-797.
(8) Peng Dai, Zihua Ma, Huizhen Xue, Kaili Xie, Yufei Li, Yafang Sun, Qing Xia, Mingzhi Zhang, Yu-Cheng Gu, Weihua Zhang*, Discovery of novel D/L-camphor derivatives containing oxime ester as fungicide candidates: Antifungal activity, structure-activity relationship and preliminary mechanistic study, Adv. Agrochem. 2024, https://doi.org/10.1016/j.aac.2024.11.007
(9) Peng Dai, Yufei Li, Yu Chen, Jian Jiao, Qingqing Wang, Chenxiao Li, Yucheng Gu, Yanbin Zhang, Qing Xia* and Wei-Hua Zhang*. (Fluoromethylsulfonyl)methylation of Quinoxalinones using NaSO2CH2F for C-F Bond Cleavage, Org. Lett., 2022, 24, 1357–1361.
(10) Peng Dai, Jian Jiao, Qingqing Wang, Xiang Yu, Peng Teng, Yuchuan Zhu, Yu-Cheng Gu, Wei-Hua Zhang*. Direct Csp2-H difluoromethylation of heterocycle by K2S2O8, Tetrahedron, 2021, 132466.
(11) Peng Dai, Chenxiao Li, Yufei Li, Qing Xia, Mingzhi Zhang, Yu-Cheng Gu, Wei-Hua Zhang*. Transition‐Metal‐Free Csp2-H Regioselective Thiocyanation of Free Anilines, Asian J. Org. Chem. 2020, 9, 1585-1588.
(12) Peng Dai, Chenxiao Li, Yufei Li, Yuchuan Zhu, Peng Teng, Yu-Cheng Gu, Wei-Hua Zhang*. Direct Difluoromethylation of Heterocycles through Photosensitized Electron Transfer, Eur. J. Org. Chem. 2022, 1-5.
(13) Peng Dai, Xin Tan, Qian Luo, Xiang Yu, Shuguang Zhang, Fang Liu* and Wei-Hua Zhang*, Synthesis of 3-Acyl-isoxazoles and △2-Isoxazolines from Methyl Ketones, Alkynes or Alkenes, and tert-Butyl Nitrite via a Csp3–H Radical Functionalization/Cycloaddition Cascade, Org. Lett., 2019, 21, 5096-5100.
(14) Peng Dai, Xiang Yu, Peng Teng, Wei-Hua Zhang* and Chao Deng*, Visible-Light- and Oxygen-Promoted Direct Csp2‑H Radical Difluoromethylation of Coumarins and Antifungal Activities, Org. Lett., 2018, 20, 6901-6905.
(15) Peng Dai, Kai Luo, Xiang Yu, Wen-Chao Yang, Lei Wu* and Wei-Hua Zhang*, Tert-Butyl Nitrite Mediated Expeditious Methylsulfoxidation of Tetrazole-amines with DMSO: Metal-free Synthesis of Antifungal Active Methylsulfinyl-1H-tetrazole Derivatives, Adv. Synth. Catal., 2018, 360, 468-473.
(16) Liu-Yu Shen, Yu Sun, Yu-Qi Wang, Bing Li, Wen-Chao Yang*, Peng Dai*. K2S2O8-promoted radical trifluoromethylthiolation /spirocyclization for the synthesis of SCF3‑featured spiro[5,5]trienones, Tetrahedron, 2022, 132649.
(17) Yufei Li, Shimin Yang, Shun Zhang, Yifan Zheng, Qingqing Wang, Peng Dai, Yucheng Gu, Weihua Zhang, * Qing Xia*. Discovery of novel 3-phenylhydrazone coumarin derivatives as potential antifungal agents against phytopathogenic fungi, Food Chemistry, 2025, 486, 144655.
(18) Yufei Li, Shimin Yang, Yifan Zheng, Shun Zhang, Qingqing Wang, Peng Dai, Jie Hou, Yucheng Gu, Weihua Zhang,* Qing Xia*, Discovery of Coumarin-7-N/O-Acethydrazide Derivatives as Novel Antifungal and Herbicidal Agents. J. Agric. Food Chem. 2025, 73, 24, 14783–14795.
(19) Hongyi Chen, Zunyun Jiang, Ziyun Mai, Yang Meng, Peng Dai, Ming-Zhi Zhang, Lei Wu, Weihua Zhang, Jinfeng Miao, Yingguang Zhu.* Design, Synthesis, Antifungal Evaluation, and Action Mechanism of Novel l-Carvone-Based Derivatives as Potential Succinate Dehydrogenase Inhibitors. J. Agric. Food Chem. 2025, 73 (17)10615–10626.
(20) Kaili Xie, Ruirui Su, Peng Dai, Qing Xia, Fang Liu*, Weihua Zhang*, and K. N. Houk. Stereoselective Oxidative Coupling of Amino Acids or Oligopeptides with Aldehydes: A Mechanism Study. J. Org. Chem. 2025, 90 (38) 13458–13466.
(21) Peng Teng, Yufei Li, Ruoyu Fang, Yuchuan Zhu, Peng Dai and Weihua Zhang*, Design, Synthesis, Antifungal Activity, and 3D-QSAR Study of Novel Quinoxaline-2-Oxyacetate Hydrazide, Molecules 2024, 29 (11), 2501.
(22) Yufei Li, Kaili Xie, Shimin Yang, Peng Dai, Jianbo Guo, Yucheng Gu, Qing Xia,* and Weihua Zhang, Visible-Light-Driven Heterocyclic Fluoroalkylation Via Electron Donor Acceptor Complexes, ChemCatChem, 2024, 16 (210), e202400675.
(23) Yufei Li, Jie Hou, Pei Zhang, Peng Dai, Yu-Cheng Gu, Qing Xia,* and Weihua Zhang*, Electron Donor-Acceptor Complex Driven PhotocatalystFree Trifluoromethylation of Heterocycles, Chem. Eur. J., 2024, 30 (31), e202400237.
(24) Zhi-Qi Zhang, Yue-Qian Sang, Cheng-Qiang Wang, Peng Dai, Xiao-Song Xue, Jared L. Piper, Zhi-Hui Peng, Jun-An Ma, Fa-Guang Zhang, Jie Wu, Difluoromethylation of Unactivated Alkenes Using Freon-22 through Tertiary Amine-Borane-Triggered Halogen Atom Transfer, J. Am. Chem. Soc., 2022, 144, 14288-14296.
(25) Qingyao Li, Peng Dai, Haidi Tang, Muliang Zhan and Jie Wu*, Photomediated reductive coupling of nitroarenes with aldehydes for amide synthesis, Chem. Sci., 2022,13(32), 9361-9365.
(26) Qing-Qing Wang, Shu-Guang Zhang, Jian Jiao, Peng Dai and Wei-Hua Zhang*. Novel Fluorinated 7-Hydroxycoumarin Derivatives Containing an Oxime Ether Moiety: Design, Synthesis, Crystal Structure and Biological Evaluation, Molecules 2021, 26, 372.
(27) Xiang Yu, Yu Chen, Qian Luo, Yufei Li, Peng Dai, Qing Xia, Fang Liu, Wei-Hua Zhang*. Selective Radical N-H Activation: The Unprecedented Harnessing of Formamide with S8 for N-S-N Bonds Construction. Asian J. Org. Chem. 2021, 10, 771-775.
(28) Qing Xia, Yufei Li, Lan Cheng, Xin Liang, Chenlin Cao, Peng Dai, Hongping Deng, Weihua Zhang*, and Qingmin Wang*, Electron Donor–Acceptor Complex-Initiated Photochemical Cyanation for the Preparation of α-Amino Nitriles, Org. Lett. 2020, 22, 9638.
(29) Shaowei Wang, Peng Dai, Chao Deng and Wei-Hua Zhang*, Metal-free, Visible-Light-Induced Radical Trifluoromethylation /Cyclization of N-benzamides with CF3SO2Na to Synthesize CF3-Containing Isoquinoline-1,3-diones. ChemistrySelect. 2019, 4, 10329-10333.
(30) Xiang Yu, Peng Dai, Yu-Chuan Zhu, Peng Teng, Wei-Hua Zhang*, Chao Deng*, Metal-free, Visible-Light-Mediated Direct Csp2-H Radical Mono- and Bis-trifluoro -methylation of Coumarins and Bioactivity Evaluation, ChemCatChem, 2018, 10, 5115-5118.
(31) Wen-Chao Yang, Peng Dai, Kai Luo, Yi-Gang Ji, and Lei Wu*, Aldehydes as Carbon Radical Acceptors: Silver Nitrate Catalyzed Cascade Decarboxylation and Oxidative Cyclization toward Dihydroflavonoid Derivatives, Adv. Synth. Catal. 2017, 359, 2390-2395.
(32) Wen-Chao Yang, Peng Dai, Kai Luo and Lei Wu*, Iodide/tert-Butyl Hydroperoxide -Mediated Benzylic C-H Sulfonylation and Peroxidation of Phenol Derivatives, Adv. Synth. Catal. 2016, 358, 3184-3190.
发明专利:
(1) 吴磊(导师);戴朋;罗凯;亚砜四氮唑衍生物及其制备方法与应用。专利号:ZL201710784802.X。